The appraisal methods refers to the systematic methodology that you are going to use to read, appraise, compare, and contrast the included evidence. Either by comparing the results of previously appraised evidence, for instance by comparing systematic literature reviews with or without meta-analysis and/or CPGs; or by critically appraising the not yet synthesized evidence using appraisal forms as the one attached as PDF file. Appraisal forms facilitate the process of assessment of the methodological quality of the found evidence. The goal is to systematically examine the research evidence to judge its applicability, validity, and quality of the evidence.